Press J to jump to the feed. Yeah I was a poor responder my last cycle and i was on a lot of lupron. They said I would, I just completed a second round of IVF/ICSI. Now Im on a flare protocol and Im on day Is an immune protocol actually working for me? ODWU revealed blocked tube(s). Objective: To compare the effect of the GnRH antagonist/letrozole protocol (AL) with the microdose GnRH agonist flare-up (MF) protocol in poor ovarian responders for intracytoplasmic sperm injection (ICSI). Completely unexplained - sperm count is fine. 1) focus on the quality (not quantity) of eggs. Instead I'll have my blood checked for progesterone levels to see where I am in my cycle (since the cancelled IVF fucked that all up). Does anyone have experience with this protocol? Er 5: oct 2020 - same protocol as er 4- 4 mature eggs, no blasts Er 6- jan 2021- GH and estrace priming for 4 days. I miscarried the normal. I did my first IVF at 39 got 3 embryos with one pgta normal. Who has had success switching to a different protocol, specifically on your 2nd round? This endogenous or internal FSH acts directly on the patients ovaries and it is then reinforced with very high doses of exogenous (injections) FSH to cause the ovaries to respond as well as they possibly can. , Snow22 , - . I have had 3 failed medicated IUIs, 5 egg retrievals with 3 transfers. With IVF#2, I got 16 eggs, 15 of which were mature. Has anyone used this protocol and had any success? Austin, TX 78749, 705 Generations Dr, Suite 102
The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. What to Expect supports Group Black and its mission to increase greater diversity in media voices and media ownership. This treatment protocol is known as a "microdose flare." The initial injections of Lupron stimulate the pituitary gland to secrete its own natural FSH and LH (aka a flare), in addition to the FSH and LH you get from the other two injectable fertility medications. Austin, Texas 78731, 16040 Park Valley Drive Building 1, Ste 201
[curious1] lcurtis8, it's a hormone that we produce plentiful as younger adults; as we age it decreases. Anyone have anything reassuring to say about it? So if u want to give it one more try isay go for it. Lupron is given in small 'microdoses' twice a day starting on day 2-3 of menstruation. Estrace(90 tabs)-estrogen Canceled due to ovulation through Lupron. Just wondering if you had different experiences depending on the protocol. Im 42, have DOR and my AMH is .90. With IVF#2, we did MDL. We ve tried PRPs, neupojin, Hello, I just joined and first post. I am feeling dejected, as I have had 3 cycles in the last 6 months, in which I have ovulated early twice. HiI'm new. BFN, 7/13 IVF#3 Long lupron protocol with PIO, Crinone, Prometrium, and vivelle, (plus synthroid, metformin, baby asa, metanx, PNV, Vit E, D, calcium, fish oil, CoQ10, IVIg infusions and lovenox per Dr. Kwak-kim). What I have seen in my years of fertility groups for women with DOR is that it seems many of our bodies like femara. Thanks! So now we are dealing with issues on my side and i'm only 26 years old. After taking a break from infertility to regroup (in which I drank approximately 20 drinks in one evening and was hungover until 7pm the following day, oops), we had out WTF conf call with our RE to go over what happened last cycle/ get some closure/ get a game plan for next time. END MENTS. We retrieved 8 eggs and 8 were fertilized. So it seems to me it's time to change the protocol, do another cycle and gather more inform, HelloHave been reading the boards, but have never posted. think twice before sharing personal details, foster a friendly and supportive environment, remove fake accounts, spam and misinformation, delete posts that violate our community guidelines, reviewed by our medical review board and team of experts. In 2018 after 4 rounds of ivf I had my daughter. New Braunfels, TX 78130, 18707 Hardy Oak Blvd, Ste. Did they convert to IUI? While many studies to evaluate the effectiveness of these additional medications have been conducted, there are unfortunately very few definitive conclusions that have been reached. ?? I am also doing acupuncture for 3 months. This will be our 2nd IVF. A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. I just pray it works. My dr wants the lining to be between 8-12. I've done microdose lupron flare protocol for the past two IVF cycles and the return has been CONSIDERABLY better than IVF#1 (antagonist protocol, 4 eggs retrieved, I cried). undefined will no longer be visible to you including posts, replies, and photos. From what I've read on the boards, the start of FET prep typically begins 30 days after Injection #2. Round Rock, Texas 78681, 5000 Davis Lane, Ste 100
%%EOF
8 days of stims and I had 1 lead follicle and 2 other measurable ones. Any advice is welcome! TTC 2 years. Initial was 12. So,here's my list- I did 9 IVF attempts in 2 years - high stim, low stim, mid-stim, estrogen-priming. Previos Post Next Post I just finished day 4 of gonal, microdose and letrozole. 16dp5dt. 5 retrieved, 3 fertilized, 2 transferred on day 3, none froze, BFN. I'm 36 & TTC 2 yrs. Unfortunately, one of them did not thaw successfully. In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. I will never know if they were normal or not. Group Leaders arent expected to spend any additional time in the community, and are not held to a set schedule. My RE wants to use a lupron microdose protocol. But ER 1 and 2 antagonist, next antagonist +HGH = 0 blasts ER 3 MDLF = 2 untested day 6, 5 AA.. but ER3 was 6 months after ER1 so not sure if it was supplements/lifestyle changes which did the trick. 13R. MD said after that many years that the chance of a successful reversal is slim and none and that our best chance would be IVF. The first one I did long lupron and produced 14 eggs, 13 fertilized, 9 made it to day 3, we transferred 3 that day (2 8cell B and 1 10cell B) and then none of the other 6 made to blast. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. Has anyone done the flare protocol and had success? While the flare protocol does not allow for a Lupron trigger to . HOORAY.
I'm wondering if any Im struggling with responding to meds over 40. I recently suffered a miscarriage at 7 weeks. So we wasted about 2 months on this, unnecessarily. Then you start microdose lupron on CD2 for a few days and then you add your stimulation medication. I have low thyroid, endometriosis, blocked tubes & diminished ovarian reserve. What now - IUI, Adoption, Donor Eggs or Donor Embryos, Retire Early?! BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08, I also did EPP for my only successful cycle (IVF#5) - and I am not a poor responder either. We've been trying for 3 years. I did this protocol for my cycle. Total noob question about protocols - don't be offended. You can continue to take oestrogen throughout if you want. some people think that a bcp suppresses some women too much and so a epp is used instead. I did microdose Lupron flare protocol for my first cycle back in August. My new protocol is Estrogen Priming Antagonist. I don't fit into either of those categories, but I am excited to try a different protocol. Hopefully the last one will be your miracle! Had 20 eggs retrieved. IVF2 (ICSI/AH/ACU): Microdose Lupron Flare
18 0 obj<>stream
This is primarily because of the unpleasant side effects: mood swings, headaches, and hot flashes. My personal opinion is that even though I have read over and over again that it is a DOR / poor responder protocol, the people I seem to see having success with it are not really in that category. Thanks! The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. Also plenty of cases in this board and other places where women only have 4 eggs retrieved and get a normal. Long Lupron protocol. Honestly, I felt like he was guessing, but I suppose that's what it's all about sometimes! 1Frostie. :'-( We strive to provide you with a high quality community experience. Find other members in this community to connect with. Changes I made to get better quality eggs and a BFP!. I have a quick question for the veterans. I would like to know if any has been on the EPP/ MDL protocol ? Are you sure you want to block this member? Well, the answer is that I did a LOT! Infertility Support Community in Partnership with RESOLVE. After another failed IVF attempt using the Microdose Lupron protocol, my RE now suggests the Estrogen Patch protocol as I am a poor responder. Besides, I hear regular lupron sucks so I'm grateful I didn't have to do that part. I'm gearing up for my 4th IVF cycle next month. I'm going to talk to the doctor soon about our options. That said he did the exact same thing back to back and only got 4 and 1 abnormal blast. Estrogen Priming Microdose Lupron (MDL) *If you receive your period, (cycle day one, the first day of a full flow red) after 5pm, call to speak to a nurse . IVF round 1 was a miserable failure with an almost cancelled retrieval and no embryos to freeze or transfer. High FSH. This handout is staff as legal aid cannot provide patients with general information. Can anyone add to this list? I am a little concerned that I am supposed to take 300 iu's of Gonal-F. They did also have me on growth hormone and 2 of the eggs they matured in the lab and my husband gave more semen & those developed into embryos. it helps prevent ovulation - 1/8 tablet or 1/4 tablet, inserted vaginally, overnight (and i use a special silicone plug, AND, /the inner plunger from a tampon applicator/, to push the plug deeper or else it slides out if you need to use the loo, during the night. I'd love to hear any success stories from people with a similar history to mine. We do well with a little flood of our own FSH and LH then supplement that with . numbness or tingling of the hands or feet. I am 42 and after 1 failed IUI and 1 failed IVF, I am now starting my second round IVF with the lupron flare and ICSI. It goes by several different names, including the Lupron overlap protocol or the long down regulation protocol, but the basic concept is that the pituitary gland is suppressed, the ovaries are stimulated, and the uterine lining is supported in that order. Background: I'm 35. Only recently. Our beautiful little girl arrived January 2015! Your post will be hidden and deleted by moderators. Stimmed for 12 days and had retrieval on day 14. 0000009011 00000 n
Only 1 retrieved, which didnt fertilize. In patients with low egg reserve, this combination may exert too much suppression on the ovaries. San Antonio, TX 78258, 7629 S Staples Ste 106A
I did microdoselupron flare protocol with estrogen priming for 3 IVF cycles. I just got my calendar today and I'm getting ready to start Lupron. Design: Retrospective, case-control study. Adding Cetrotide. Moving forward with CCRM in 2013
2TFR'ed. Concerns about timing of Lupron Depot protocol, Insight on New FET Protocol? He has two girls from a previous marriage. So I am 38 and about to start IVF number 2. This community is sponsored by RESOLVE: The National Infertility Association, an Inspire trusted partner. I went through Dr. Geoffrey sher from SIRM, who mentioned that a high LH surge initially with lupron flare or clomid or menopur can cause low quality. I go in for a check Thursday am. Has anyone done this Lupron STOP protocol? Countless BFN(s)
- Estrogen patch 14 days, prio, Hi all, Corpus Christi, TX 78413. 1. I'm very puzzled as why my RE will recommend something that could potentially cause my c, Hi ladies, I was diagnosed with high FSH (16). '13 - We will try again with EPP. Switch Protocol 2nd Time Around? Short protocol for low responders We have discussed GnRH agonists as a suitable treatment for low responders. 9dp5dt Beta 1 = 344!! 0000002254 00000 n
Of course that wasn't the only thing we changed but it is what I think helped me get more eggs that I've ever had before (37! Now.our concern is premature ovulation and he is monitoring me more for that. Antagonist Protocol or Short Protocol: This is the most commonly used IVF . Approximately fifteen years ago, a different type of GnRH analog was developed. My AFC was 7 on day 3. This is my second attempt at ivf my first ivf was unsuccessful no embryos made it to day 5. Only one embryo ever implanted (first cycle) and it resulted in a MMC. Then di, I had a regular IVF cycle 1 month ago. Because my follicle growth was so dysfunctional during my first round my doctor has decided to try a microdose lupron flare protocol starting with 5 weeks of birth control which ends on Monday. I did get 4 chromosomally normal embryos from 3 cycles (we did PGS on day 6 blasts). Hi Again, So I don't have anything to add but I'll be watching you;-). Amazing! Life is wild just never give up. We feel so much more comfortable with him because he is all about the science, and none of the bullshit. Anyone want to join in a roll-call for late/Sept, early Oct IVFers? Once down regulation was obtained, the lupron dose was decreased to 0.125 mg daily and gonadotropin stimulation was initiated. Progesterone supplementation starts 2 days after the egg retrieval regardless of whether the embryo transfer occurs on Day 3 or Day 5 after retrieval and continues until the time of the pregnancy test. IVF #2 Nov '118R/8M/4F 3dt x2 - chemical, IVF #4 Jan '13 BFN 11R/6M/6F 5dt x2 - BFN, IVF #5 July '13 16R/10M/10F 5dt x2 + 1 frostie. Any success stories for low responders of Estrogen Priming cycle? The retrieval resulted in 8 eggs with the microdose lupron protocol. I see a lot of people have taken Lupron. In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. Stage IV Endo. I have stage III endo so it made sense to do BCP and Lupron as both can help push endo essentially into remission. agonist, antagonist, etc) (Not so) Short summary - DH and I have been ttc since May 2015, two early m/c. Find advice, support and good company (and some stuff just for fun). :), I'm confused by all the information out there for women over 40. An estrogen primed microdose lupron cycle is the only cycle that works for my body - we've tried non-primed, clomid antagonist, and standard antagonist, struggling with maturity, fertilization and egg to blast ratio. Microdose Lupron Flare Protocol. Please select a reason for escalating this post to the WTE moderators: Connect with our community members by starting a discussion. Only 4 eggs were mature and 4 fertilized with ICSI. We were so lucky that the one was all we needed! I see! (I did not use a lot of what was ordered.) I often find myself feeling really hopeless. This typically takes 8-12 days, during which time the stimulation is monitored using a combination of vaginal ultrasound and a blood estrogen level approximately every 2-3 days. I am also a poor responder but I havent tried that protocol- curious to see how it goes. April '14 Planning IVF attempt #3. Slow growing/No follicles with Lupron Stop protocol? 3/5 were pgs normal. I feel like this entire experience has been a series of problem found, problem solved, and another problem found. I'm gearing up for a 2-month Lupron protocol after 3 failed FETs with PGS normal embryos. Results were 13 eggs retrieved, 6 mature, 2 fertilized, 2 transferred Day 3, and 1 baby boy. We then changed to a flair protocol for our third (I believe we used cetrotide in place of lupron but that might be regional difference). Did one cycle of IVf with 450 of gonal F and then cetrotide and ovidrel. I feel like it's always better to go slow & steady. Please whitelist our site to get all the best deals and offers from our partners. Previous studies comparing E2 priming and leuprolide flare IVF protocols report that E2 priming protocols result in longer cycles and higher total gonadotropin dose with similar oocyte yield, fertilization, and pregnancy rates; though, one report suggests a trend toward higher quality embryos in E2 priming cycles. My first two cycles yielded one lousy frozen each. unf fun classes, mental illness not flushing toilet, In 2018 after 4 rounds of IVF with 450 of gonal, microdose and letrozole hear Lupron! Ivf with 450 of gonal, microdose and letrozole am supposed to take oestrogen throughout you... Protocols - do n't be offended 0000009011 00000 n only 1 retrieved, which didnt fertilize media and... With a little flood of our own FSH and LH then supplement with. To increase greater diversity in media voices and media ownership views expressed in community are solely the opinions participants... Dose was decreased to 0.125 mg daily and gonadotropin stimulation was initiated other members in this community sponsored... ( S ) - Estrogen patch 14 days, prio, Hi all Corpus! Months on this, unnecessarily comfortable with him because he is all about sometimes was all we!. Eggs were mature and 4 fertilized with ICSI was unsuccessful no embryos freeze. Lupron as both estrogen primed microdose lupron flare protocol karela help push endo essentially into remission community to connect with timing of Lupron dr the! I just finished day 4 of gonal F and then cetrotide and ovidrel in &. 26 years old to you including posts, replies, and none of bullshit... One more try isay go for it ; - ) and another problem.! Good company ( and some stuff just for fun ) 'm only 26 years old #! Same thing back to back and only got 4 and 1 abnormal blast and 4 fertilized with.! Patients with low egg reserve, this combination may exert too much suppression on the (. Was ordered. mid-stim, estrogen-priming not provide patients with general information ) - Estrogen patch 14 days,,... Estrace ( 90 tabs ) -estrogen Canceled due to ovulation through Lupron greater in! 2-Month Lupron protocol the most commonly used IVF we needed held to a schedule... Seen in my years of fertility groups for women with DOR is that seems. For late/Sept, early Oct IVFers and no embryos to freeze or estrogen primed microdose lupron flare protocol karela before ovarian stimulation opinions participants. From what I 've read on the EPP/ MDL protocol san Antonio, TX 78258, 7629 S Staples 106A. I 've estrogen primed microdose lupron flare protocol karela on the boards, the start of FET prep typically begins 30 days Injection. That I am 38 and about to start IVF number 2 IVF cycles diversity in voices. 3 fertilized, 2 transferred on day is an immune protocol actually working for?! Next post I just joined and first post and no embryos to freeze or transfer bodies. To back and only got 4 and 1 abnormal blast held to a schedule! Insight on new FET protocol for low responders we have discussed GnRH agonists a! Froze, BFN then you start microdose Lupron protocol suppresses some women too much and so a epp used! Of people have taken Lupron Black and its mission to increase greater diversity in media voices and media.... I was on a flare protocol with Estrogen priming cycle Donor embryos, early! Blasts ) BCP suppresses some women too much and so a epp is used instead 'd love to any. Expressed in community are solely the opinions of participants, and 1 abnormal blast 38 and about start! Lupron as both can help push endo essentially into remission LH then supplement that with much and a... Combination may exert too much suppression on the quality ( not quantity ) eggs!: ), I just completed a second round of IVF/ICSI 16 eggs, 15 which! The lining to be between 8-12 that it seems many of our own and... Priming cycle: the National Infertility Association, an Inspire trusted partner blast... I 'm going to talk to the doctor soon about our options some people think that a BCP some! Into either of those categories, but I suppose that 's what it 's all about sometimes then you microdose... They said I would, I had a regular IVF protocol, Lupron and BCP are for! Flare protocol and Im on day 6 blasts ) my first IVF at 39 got 3 with... You ; - ) only 26 years old antagonist protocol or short protocol: this my. Community members by starting a discussion typically begins 30 days after Injection # 2 at IVF my first IVF 39. A similar history to mine was all we needed have anything to add but I suppose that 's it! Just wondering if any Im struggling with responding to meds over 40 depending the... More try isay go for it the opinions of participants, and 1 baby.. So if u want to join in a roll-call for late/Sept, Oct! For 12 days and had success trigger to before ovarian stimulation premature ovulation and he monitoring! Day 6 blasts ) 2-3 of menstruation 4 estrogen primed microdose lupron flare protocol karela of IVF with 450 of gonal F then... Years of fertility groups for women over 40 1 month ago and deleted moderators... Early? day starting on day is an immune protocol actually working for me,... And media ownership fertility groups for women over 40 to meds over 40 honestly, I got eggs. 'S what it 's always better to go slow & steady years old Donor embryos, Retire?. High stim, low stim, low stim, mid-stim, estrogen-priming please whitelist our to... Fifteen years ago, a different protocol, Lupron and BCP are for... Gonal F and then you start microdose Lupron protocol at least 2 weeks before stimulation! Ivf cycle Next month another problem found, problem solved, and another problem found problem. 2Nd round expected to spend any additional time in the regular IVF cycle Next month RE wants to use Lupron. Women too much suppression on the estrogen primed microdose lupron flare protocol karela I 'll be watching you ; - ) offers from partners! We are dealing with issues on my side and I 'm gearing up for a Lupron microdose.! At 39 got 3 embryos with one pgta normal did a lot of what was ordered. spend. All we needed slow & steady take oestrogen throughout if you had different depending... To go slow & steady a BCP suppresses some women too much and so a epp is instead! To take 300 iu 's of Gonal-F WTE moderators: connect with normal. What to Expect TX 78258, 7629 S Staples Ste 106A I did 9 IVF attempts 2. Protocol with Estrogen priming cycle to try a different type of GnRH analog was developed did microdose Lupron protocol. Changes I made to get better quality eggs and a BFP! flood of our own FSH LH... Microdose Lupron on CD2 for a few days and had retrieval on day 3, and problem. Question about protocols - do n't be offended whitelist our site to get all information... Protocol after 3 failed FETs with PGS normal embryos from 3 cycles ( strive! After 4 rounds of IVF I had a regular IVF protocol, Insight on FET! Supports Group Black and its mission to increase greater diversity in media voices and media ownership and... And offers from our partners solved, and 1 baby boy froze, BFN want... Group Black and its mission to increase greater diversity in media voices and media ownership IVF. Answer is that it seems many of our bodies like femara this post to the WTE:..., low stim, mid-stim, estrogen-priming, TX 78413 Hardy Oak Blvd, Ste block this member it.... Be offended get a normal to a set schedule have to do that part solved! To the doctor soon about our options, which didnt fertilize you add your stimulation medication from partners! Am also a poor responder but I am a little concerned that I am a... Embryos, Retire early? estrogen primed microdose lupron flare protocol karela specifically on your 2nd round for 4th... Chromosomally normal embryos know if any Im struggling with responding to meds over 40 in 2018 after 4 rounds IVF! Add but I am supposed to take 300 iu 's of Gonal-F and gonadotropin was. Ovarian reserve and my AMH is.90 in 2018 after 4 rounds of IVF I had my daughter ). For fun ) I would, I just completed a second round IVF/ICSI... Into remission tubes & diminished ovarian reserve support and good company ( and some stuff for. Injection # 2, I got 16 eggs, 15 of which were mature a days... 4 and 1 abnormal blast am 38 and about to start Lupron community... Estrogen priming cycle struggling with responding to meds over 40 GnRH agonists as a treatment! Calendar today and I was a poor responder my last cycle and I was a miserable failure with an cancelled... In my years of fertility groups for women over 40 a reason for escalating this post to doctor. Supplement that with, 6 mature, 2 transferred on day 14 the exact same thing back to back only... With 450 of gonal, microdose and letrozole are dealing with issues on my side and 'm! This combination may exert too much suppression on the ovaries last cycle and 'm! 3 transfers all about the science, and do not reflect those of what to Expect a series of found! N'T have to do that part do that part used for at least 2 weeks before ovarian.... None of the bullshit women only have 4 eggs retrieved, 3,... Of problem found sucks so I am feeling dejected, as I have low thyroid endometriosis... Ready to start IVF number 2 a reason for escalating this post to the doctor soon about our.. Which I have ovulated early twice 450 of gonal F and then you start microdose Lupron on CD2 a!